
MolluscDB: an integrated functional and evolutionary genomics database for the hyper-diverse animal phylum Mollusca
Paul
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Mollusca represents the second largest animal phylum however stays poorly explored from a genomic perspective. Whereas the latest enhance in genomic sources holds nice promise for a deep understanding of molluscan biology and evolution, entry and utilization of those sources nonetheless pose a problem. Right here, we current the primary complete molluscan genomics database, MolluscDB , which compiles and integrates present molluscan genomic/transcriptomic sources and offers handy instruments for multi-level integrative and comparative genomic analyses.
MolluscDB allows a scientific view of genomic info from varied elements, comparable to genome meeting statistics, genome phylogenies, fossil data, gene info, expression profiles, gene households, transcription components, transposable parts and mitogenome group info. Furthermore, MolluscDB provides beneficial custom-made datasets or sources, comparable to gene coexpression networks throughout varied developmental levels and grownup tissues/organs, core gene repertoires inferred for main molluscan lineages, and macrosynteny evaluation for chromosomal evolution.
MolluscDB presents an integrative and complete genomics platform that can enable the molluscan neighborhood to deal with ever-growing genomic sources and can expedite new scientific discoveries for understanding molluscan biology and evolution.
A Causality Perspective of Genomic Breed Composition for Composite Animals
Genomic breed composition (GBC) of a person animal refers back to the partition of its genome in response to the inheritance from its ancestors or ancestral breeds. For crossbred or composite animals, realizing their GBC is helpful to estimate heterosis, to characterize their precise inheritance from basis breeds, and to make administration selections for crossbreeding applications. Numerous statistical approaches have been proposed to estimate GBC in animals, however the interpretations of estimates have various with these strategies. Within the current research, we proposed a causality interpretation of GBC primarily based on path evaluation.
We utilized this technique to estimating GBC in two composite breeds of beef cattle, particularly Brangus and Beefmaster. Three SNP panels have been used to estimate GBC: a 10Ok SNP panel consisting of 10,226 frequent SNPs throughout three GeneSeek Genomic Profiler (GGP) bovine SNP arrays (GGP 30Ok, GGP 40Ok, and GGP 50Ok), and two subsets (1K and 5K) of uniformly distributed SNPs. The trail evaluation decomposed the relationships between the ancestors and the composite animals into direct and oblique path results, and GBC was measured by the relative ratio of the coefficients of direct (D-GBC) and mixed (C-GBC) results from every ancestral breed to the progeny, respectively.

Estimated GBC various solely barely between totally different genotyping platforms and between the three SNP panels. Within the Brangus cattle, as a result of the 2 ancestral breeds had a really distant relationship, the estimated D-GBC and C-GBC have been comparable to one another within the path evaluation, and so they corresponded roughly to the estimated GBC from the linear regression and the admixture mannequin.
Within the Beefmaster, nevertheless, the robust relationship in allelic frequencies between Hereford and Shorthorn imposed a problem for the linear regression and the admixture mannequin to estimated GBC reliably. As an alternative, D-GBC by the trail evaluation included solely direct ancestral results, and it was strong to bias attributable to excessive genomic correlations between reference (ancestral) breeds.
Genomic Options of Parthenogenetic Animals
Evolution with out intercourse is predicted to impression genomes in quite a few methods. Case research of particular person parthenogenetic animals have reported peculiar genomic options that have been advised to be brought on by their mode of replica, together with excessive heterozygosity, a excessive abundance of horizontally acquired genes, a low transposable ingredient load, or the presence of palindromes. We systematically characterised these genomic options in revealed genomes of 26 parthenogenetic animals representing a minimum of 18 unbiased transitions to asexuality.
Surprisingly, not a single function was systematically replicated throughout a majority of those transitions, suggesting that beforehand reported patterns have been lineage-specific slightly than illustrating the overall penalties of parthenogenesis. We discovered that solely parthenogens of hybrid origin have been characterised by excessive heterozygosity ranges. Parthenogens that weren’t of hybrid origin seemed to be largely homozygous, unbiased of the mobile mechanism underlying parthenogenesis.
General, regardless of the significance of recombination price variation for the evolution of sexual animal genomes, the genome-wide absence of recombination doesn’t seem to have had the dramatic results that are anticipated from classical theoretical fashions. The explanations for this are in all probability a mix of lineage-specific patterns, the impression of the origin of parthenogenesis, and a survivorship bias of parthenogenetic lineages.
Comparative Genomic Evaluation of 450 Strains of Salmonella enterica Remoted from Diseased Animals
Salmonella is a number one explanation for bacterial infections in animals and people. We sequenced a group of 450 Salmonella strains from diseased animals to raised perceive the genetic make-up of their virulence and resistance options. The presence of Salmonella pathogenicity islands (SPIs) various by serotype. S. Enteritidis carried essentially the most SPIs (n = 15), whereas S. Mbandaka, S. Cerro, S. Meleagridis, and S. Havana carried the least (n = 10). S. Typhimurium, S. Choleraesuis, S. I 4,5,12:i:-, and S. Enteritidis every contained the spv operon on IncFII or IncFII-IncFIB hybrid plasmids. Two S. IIIa carried a spv operon with spvD deletion on the chromosome.
Twelve plasmid varieties together with 24 hybrid plasmids have been recognized. IncA/C was continuously related to S. Newport (83%) and S. Agona (100%) from bovine, whereas IncFII (100%), IncFIB (100%), and IncQ1 (94%) have been seen in S. Choleraesuis from swine. IncX (100%) was detected in all S. Kentucky from hen. A complete of 60 antimicrobial resistance genes (ARGs), 4 disinfectant resistances genes (DRGs) and 33 heavy metallic resistance genes (HMRGs) have been recognized.
Recombinant Human Glutaminase kidney isoform, mitochondrial |
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MBS969526-5x1mgEColi | MyBiosource | 5x1mg(E-Coli) | EUR 8405 |
Recombinant Human Glutaminase kidney isoform, mitochondrial |
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MBS969527-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 320 |
Recombinant Human Glutaminase kidney isoform, mitochondrial |
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MBS969527-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 520 |
Recombinant Human Glutaminase kidney isoform, mitochondrial |
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MBS969527-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1925 |
Recombinant Human Glutaminase kidney isoform, mitochondrial |
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MBS969527-5x1mgEColi | MyBiosource | 5x1mg(E-Coli) | EUR 8405 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-1mg |
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QP6095-ec-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-10ug |
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QP6095-ec-10ug | EnQuireBio | 10ug | EUR 326.4 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-50ug |
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QP6095-ec-50ug | EnQuireBio | 50ug | EUR 434.4 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-100ug |
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QP6095-ec-100ug | EnQuireBio | 100ug | EUR 685.2 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-200ug |
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QP6095-ec-200ug | EnQuireBio | 200ug | EUR 1077.6 |
Recombinant Human Glutaminase kidney isoform, GST, E.coli-500ug |
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QP6095-ec-500ug | EnQuireBio | 500ug | EUR 1816.8 |
Glutaminase kidney isoform, mitochondrial |
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AP79068 | SAB | 1mg | EUR 2640 |
Glutaminase kidney isoform, mitochondrial |
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AP83270 | SAB | 1mg | EUR 2640 |
Glutaminase kidney isoform, mitochondrial |
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AP83568 | SAB | 1mg | EUR 2640 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS),partial |
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CSB-EP009528HU(F) | Cusabio | 1269 mg | Ask for price |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS),partial |
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CSB-EP009528HU(F)-20ug | Cusabio | 20ug | Ask for price |
Description: 370-669aa |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS),partial |
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CSB-EP009528HU(F1) | Cusabio | 1270 mg | Ask for price |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS),partial |
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CSB-EP009528HU(F1)-20ug | Cusabio | 20ug | Ask for price |
Description: 616-669aa |
Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial |
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AP74300 | SAB | 1mg | EUR 2826 |
Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial |
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AP74310 | SAB | 1mg | EUR 2826 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423880-002mg | MyBiosource | 0.02mg | EUR 380 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423880-01mg | MyBiosource | 0.1mg | EUR 650 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423880-1mg | MyBiosource | 1mg | EUR 2525 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423880-5x1mg | MyBiosource | 5x1mg | EUR 11205 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423890-002mg | MyBiosource | 0.02mg | EUR 380 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423890-01mg | MyBiosource | 0.1mg | EUR 650 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423890-1mg | MyBiosource | 1mg | EUR 2525 |
Recombinant Human Glutaminase kidney isoform, mitochondrial (GLS), partial |
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MBS9423890-5x1mg | MyBiosource | 5x1mg | EUR 11205 |
Rat Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2880116-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Rat Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2880116-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Rat Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2880116-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Rat Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2880116-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Rat Glutaminase kidney isoform, mitochondria,GLS ELISA KIT |
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JOT-EK1984Ra | Jotbody | 96 wells | Ask for price |
Description: Rat |
Rat Glutaminase kidney isoform, mitochondria,GLS ELISA KIT |
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E1984Ra-1096T | Jiaxing Korain Biotech Ltd (BT Labs) | 10*96T | EUR 4122 |
Rat Glutaminase kidney isoform, mitochondria,GLS ELISA KIT |
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E1984Ra-48wells | Jiaxing Korain Biotech Ltd (BT Labs) | 48 wells | EUR 300 |
Rat Glutaminase kidney isoform, mitochondria,GLS ELISA KIT |
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E1984Ra-596T | Jiaxing Korain Biotech Ltd (BT Labs) | 5*96T | EUR 2061 |
Rat Glutaminase kidney isoform, mitochondria,GLS ELISA KIT |
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E1984Ra-96wells | Jiaxing Korain Biotech Ltd (BT Labs) | 96 wells | EUR 458 |
Rat Glutaminase kidney isoform, mitochondria, GLS ELISA Kit |
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MBS1604865-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3955 |
Rat Glutaminase kidney isoform, mitochondria, GLS ELISA Kit |
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MBS1604865-48StripWells | MyBiosource | 48-Strip-Wells | EUR 305 |
Rat Glutaminase kidney isoform, mitochondria, GLS ELISA Kit |
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MBS1604865-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2005 |
Rat Glutaminase kidney isoform, mitochondria, GLS ELISA Kit |
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MBS1604865-96StripWells | MyBiosource | 96-Strip-Wells | EUR 475 |
ELISA Kit for Rat Glutaminase kidney isoform, mitochondrial |
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E15055r | EIAab | 96T | EUR 387.4 |
Rat Glutaminase kidney isoform mitochondrial, Gls ELISA KIT |
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ELI-12701r | Lifescience Market | 96 Tests | EUR 1063.2 |
Rat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607505-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3290 |
Rat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607505-48StripWells | MyBiosource | 48-Strip-Wells | EUR 295 |
Rat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607505-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1800 |
Rat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607505-96StripWells | MyBiosource | 96-Strip-Wells | EUR 450 |
Rat Gls (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7614948-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Rat Gls (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7614948-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Rat Gls (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7614948-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Rat Gls (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7614948-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Rat Glutaminase kidney isoform,mitochondria, GLS GENLISA ELISA |
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KLR1984 | Krishgen | 1 x 96 wells | EUR 341 |
Human Glutaminase kidney isoform, mitochondrial (GLS) |
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1-CSB-EP009528HU(F) | Cusabio |
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Description: Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial expressed in E.coli |
Human Glutaminase kidney isoform, mitochondrial (GLS) |
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1-CSB-EP009528HU(F1) | Cusabio |
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Description: Recombinant Human Glutaminase kidney isoform, mitochondrial(GLS),partial expressed in E.coli |
Gls ELISA Kit| Rat Glutaminase kidney isoform, mitochondrial EL |
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EF018741 | Lifescience Market | 96 Tests | EUR 826.8 |
Glutaminase Kidney Isoform, Mitochondrial (GLS) Antibody |
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abx234518-100g | Abbexa | 100 µg | EUR 350 |
Glutaminase Kidney Isoform, Mitochondrial (GLS) Antibody |
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abx234518-100ug | Abbexa | 100 ug | EUR 577.2 |
Glutaminase Kidney Isoform, Mitochondrial (GLS) Antibody |
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abx234519-100g | Abbexa | 100 µg | EUR 350 |
Glutaminase Kidney Isoform, Mitochondrial (GLS) Antibody |
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abx234519-100ug | Abbexa | 100 ug | EUR 610.8 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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EK3615 | SAB | 96 tests | EUR 739 |
Mouse Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2885936-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Mouse Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2885936-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Mouse Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2885936-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Mouse Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2885936-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2884802-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4630 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2884802-48StripWells | MyBiosource | 48-Strip-Wells | EUR 440 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2884802-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2480 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS2884802-96StripWells | MyBiosource | 96-Strip-Wells | EUR 580 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS760825-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS760825-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS760825-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS760825-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS9427449-5x96Tests | MyBiosource | 5x96Tests | EUR 3385 |
Human Glutaminase kidney isoform, mitochondrial ELISA Kit |
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MBS9427449-96Tests | MyBiosource | 96Tests | EUR 735 |
Goat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606454-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3545 |
Goat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606454-48StripWells | MyBiosource | 48-Strip-Wells | EUR 310 |
Goat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606454-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1940 |
Goat Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606454-96StripWells | MyBiosource | 96-Strip-Wells | EUR 475 |
Human GLS(Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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EKF59189-48T | Biomatik Corporation | 48T | EUR 396.9 |
Human GLS(Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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EKF59189-5x96T | Biomatik Corporation | 5x96T | EUR 2693.25 |
Human GLS(Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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EKF59189-96T | Biomatik Corporation | 96T | EUR 567 |
Human GLS(Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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EH1742 | FN Test | 96T | EUR 681.12 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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EIA07194h | Enlibio | each | EUR 430 |
Human GLS/ Glutaminase kidney isoform, mitochondrial ELISA Kit |
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E1023Hu | Sunlong | 1 Kit | EUR 515 |
Description: GLS1,KIAA0838,K-glutaminase,L-glutamine amidohydrolase |
ELISA Kit for Human Glutaminase kidney isoform, mitochondrial |
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E15055h | EIAab | 96T | EUR 441.6 |
ELISA Kit for Mouse Glutaminase kidney isoform, mitochondrial |
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E15055m | EIAab | 96T | EUR 387.4 |
Mouse Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606488-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3290 |
Mouse Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606488-48StripWells | MyBiosource | 48-Strip-Wells | EUR 295 |
Mouse Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606488-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1800 |
Mouse Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2606488-96StripWells | MyBiosource | 96-Strip-Wells | EUR 450 |
Human Glutaminase kidney isoform, mitochondrial, GLS ELISA Kit |
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MBS2602981-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3040 |
Human Glutaminase kidney isoform, mitochondrial, GLS ELISA Kit |
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MBS2602981-48StripWells | MyBiosource | 48-Strip-Wells | EUR 285 |
Human Glutaminase kidney isoform, mitochondrial, GLS ELISA Kit |
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MBS2602981-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1670 |
Human Glutaminase kidney isoform, mitochondrial, GLS ELISA Kit |
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MBS2602981-96StripWells | MyBiosource | 96-Strip-Wells | EUR 405 |
Mouse GLS (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7615355-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Mouse GLS (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7615355-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Mouse GLS (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7615355-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Mouse GLS (Glutaminase kidney isoform, mitochondrial) ELISA Kit |
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MBS7615355-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Human Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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NSL1245Hu | Sunlong | 96 wells | EUR 468 |
Description: Sandwich ELISA |
Human Glutaminase kidney isoform, mitochondrial (GLS) ELISA Kit |
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RK11040 | Abclonal | 96T | EUR 322.37 |
Bovine Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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MBS2610421-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3545 |
Bovine Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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MBS2610421-48StripWells | MyBiosource | 48-Strip-Wells | EUR 310 |
Bovine Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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MBS2610421-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1940 |
Bovine Glutaminase kidney isoform mitochondrial(GLS) ELISA Kit |
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MBS2610421-96StripWells | MyBiosource | 96-Strip-Wells | EUR 475 |
Canine Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607260-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3545 |
Canine Glutaminase kidney isoform mitochondrial (GLS) ELISA Kit |
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MBS2607260-48StripWells | MyBiosource | 48-Strip-Wells | EUR 310 |
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The Salmonella strains from sick animals contained varied SPIs, resistance genes and plasmid varieties primarily based on the serotype and supply of the isolates. Such sophisticated genomic constructions make clear the pressure traits contributing to the severity of illness and therapy failures in Salmonella infections, together with these inflicting diseases in animals.
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