The EDA deficient mouse has Zymbal’s gland hypoplasia and acute otitis externa

In mice, rats, dogs and humans the growth and function of sebaceous glands and eyelid Meibomian glands depend on the ectodysplasin signalling pathway. Mutation of genes encoding the ligand EDA, its transmembrane receptor EDAR, and the intracellular signal transducer EDARADD leads to Hypohidrotic Ectodermal Dysplasia characterised by impaired development of teeth and hair as well as…

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Genomic, Transcriptomic and Epigenomic Tools to Study the Domestication of Plants and Animals: A Field Guide for Beginners

Genomic, Transcriptomic and Epigenomic Tools to Study the Domestication of Plants and Animals: A Field Guide for Beginners

Within the final decade, genomics and the associated fields of transcriptomics and epigenomics have revolutionized the examine of the domestication course of in vegetation and animals, resulting in new discoveries and new unresolved questions. Provided that some domesticated taxa have been extra studied than others, the extent of genomic knowledge can vary from huge to…

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